Advising the National Institutes of Health on rigor and reproducibility in research with nonhuman animals

With substantial input from the Committee on Animal Research and Ethics, APA submitted comments (PDF, 118KB) to the National Institutes of Health (NIH) Request for Information on enhancing rigor, transparency and translatability to improve biomedical research involving animal models (NOT-OD-20-130). APA emphasized that the problems of rigor, transparency and translatability beset all basic and preclinical research—not just research with nonhuman animals. The solutions NIH is proposing to remedy these shortcomings, including requiring preregistration of hypotheses and research designs for nonhuman animal research studies only, will not likely produce the desired outcome. APA Science and Advocacy staff will continue to monitor developments as the regulatory process plays out.

For more information contact Sangeeta Panicker, PhD.